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The chemical of concern is toluenethat is a possible

01 / 10 / 2021 Others

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Question


My question deals with toxicology: "You have been asked to complete a screening level risk assessment to compare routes of chemical exposure and to determine whether it poses a health risk."


"The receptor is a 75kg man who has worked 9 hours a day as a mechanic for 20 years. The chemical of concern is toluenethat is a possible carcinogenand is a constituent of gasoline as well as auto mobile exhaust gas"


 Calculate Estimated Daily Intake (EDI) for the two following routes of exposure:


Inhalation with an air concentration of 52.0 g/m3 during work time for 20 years


Skin transfer through the grease that covers his hands during work time (occupational exposure)


PART B : Calculate the relative margin of safety (RMOS) "Is it OK?"



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