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a) Approximately how deep can confocal microscopy work deep in human tissue and what physical mechanism is dominant in this limitation.

01 / 10 / 2021 Medical

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Several methods are used for imaging in medicine. 

a)    Approximately how deep can confocal microscopy work deep in human tissue and what physical mechanism is dominant in this limitation.
b)    Briefly describe one optical imaging method used to avoid scattering in human tissue.
c)    Sketch a graph of resolution v imaging depth including confocal microscopy, OCT, Ultrasound, X-Ray CT, MRI and PET.
d)    What limits the resolution ion X-Ray CT?

Question 2

a)    Describe, with the aid of a diagram, the operation of a photoacoustic imaging system. 
b)    How does a photoacoustic system facilitate the measurement of melanoma depth?
c)    Describe one other measurement which photoacoustics can do, but which is not possible with ultrasound.

 
 
Question 3

a)    Describe, with the aid of diagrams, the one form of Fourier domain optical coherence tomography and give at least one advantage and one disadvantage over time domain optical coherence tomography.
b)    Briefly explain A-Scans are obtained.
c)    Briefly explain how B- and C-Scans are obtained. 
d)    What limits the imaging depth in optical coherence tomography?


Question 4.


a)    Describe one method of reducing light scattering in human tissue.
b)    What are the advantages of using this method?
c)    What are the disadvantages of using this method?



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