This paper circulates around the core theme of a) A diagram and brief introduction to the disease and how the mutation gives rise to it together with its essential aspects. It has been reviewed and purchased by the majority of students thus, this paper is rated 4.8 out of 5 points by the students. In addition to this, the price of this paper commences from £ 99. To get this paper written from the scratch, order this assignment now. 100% confidential, 100% plagiarism-free.
CRISPR-Cas9 gene editing by NHEJ is generally more efficient than HDR, but correction of point mutations in an open reading frame is only really feasible by HDR. However, a recent paper (He 2016) describes a new method for inserting DNA segments into the genome at precise regions by NHEJ.
Question
In a genetic disease of your choice (except CF), outline a protocol to correct a known mutation that causes that disease.Structure your answer as follows:
a) A diagram and brief introduction to the disease and how the mutation gives rise to it
