This paper circulates around the core theme of 1. What organ is most at risk for toxicity in acetaminophen overdose? together with its essential aspects. It has been reviewed and purchased by the majority of students thus, this paper is rated 4.8 out of 5 points by the students. In addition to this, the price of this paper commences from £ 99. To get this paper written from the scratch, order this assignment now. 100% confidential, 100% plagiarism-free.
A 24-year-old female was seen in the Emergency Department. She stated that she had ingested approximately 25 acetaminophen tablets (500 mg each) six hours earlier in a suicide attempt following an argument with her husband. She later became frightened and drove herself to the ED. She stated that no other medications or alcohol had been ingested.
1. What organ is most at risk for toxicity in acetaminophen overdose?
2. What chemistry laboratory values would be most useful to confirm this potential organ damage?
3. The patient’s acetaminophen level was 265 g/mL. Is she at risk for developing hepatic necrosis?
4. What specific antidotal therapy should be administered? What is the most crucial time period for administration?
5. How is acetaminophen measured in the laboratory?
6. Give one proprietary name of this drug.
7. If the half life of the drug is 5 hours, how many hours would it take to achieve steady state if the drug was taken for therapeutic purposes?
8. To what class of drugs does acetaminophen belong? Name one other drug in this class.
9. What are the two main therapeutic actions of acetaminophen?
